Q&A: Recently diagnosed with Hep C. very discouraged depending on genotype I have. I am not sure yet still testing.

Question by CASTEEL L: Recently diagnosed with Hep C. very discouraged depending on genotype I have. I am not sure yet still testing.
I hear there is only 30-40% cure rate.This is not good. I would like to get opinions of the 60% of unsuccessful treatments as to why this is, Are these people not following instructions per doctors order, still drinking, doing drugs, race, age, etc.?Have there been any studies done on this?

Best answer:

Answer by bmac
Sounds to me, from your posting history, that you just refuse to believe that you contracted Hepatitis C. You keep wanting more tests. More opinions. There is no cure for Hep. C. None. It can be treated and it is possible for it to go into remission, but no cure.


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Q&A: Recently diagnosed with Hep C. very discouraged depending on genotype I have. I am not sure yet still testing. — 2 Comments

  1. 1. Should treatment with pegylated ribivirin-interferon not return a 2-log viral reduction or complete clearance of RNA (termed early virological response) after 12 weeks for genotype 1, the chance of treatment success is less than 1%.

    2. Early virological response is typically not tested for in non-genotype 1 patients, as the chances of attaining it are greater than 90%. The mechanism of action is not entirely clear, because even patients who appear to have had a sustained virological resonse still have actively replicating virus in their liver and peripheral blood mononuclear cells.
    This is one of the big issues.

    3. Treatment during the acute infection phase has much higher success rates (greater than 90%) with a shorter duration of treatment (but balance this against the 80% chance of spontaneous clearance without treatment).

    4. Those with low initial viral loads respond much better to treatment than those with higher viral loads (greater than 2 million virons/ml).

    5. The current combination therapy is usually supervised by physicians in the fields of gastroenterology, hepatology or infectious disease.This treatment may be physically demanding, particularly those with a prior history of drug or alcohol abuse. It can qualify for temporary disability in some cases.

    6. A substantial proportion of patients will experience a panoply of side effects ranging from a ‘flu-like’ syndrome (the most common, experienced for a few days after the weekly injection of interferon) to severe adverse events including anemia, cardiovascular events and psychiatric problems such as suicide or suicidal ideation. The latter are exacerbated by the general physiological stress experienced by the patient.

    7. Another aspect worth mentioning here is In addition to the standard treatment with interferon and ribavirin, several studies have shown higher success rates when the antiviral drug amantadine (Symmetrel) is added to the regimen. Sometimes called “triple therapy”, it involves the addition of 100mg of amantadine twice a day. Studies indicate that this may be especially helpful for “nonresponders” – patients who have not been successful in previous treatments using interferon and ribavirin only.
    8. Unfortunatly, amantadine is not approved for treatment of Hepatitis C, and studies are ongoing to determine when it is most likely to benefit the patient.

    9. Guidelines strongly recommend that hepatitis C patients be vaccinated for hepatitis A and B if they have not yet been exposed to these viruses, as this would radically worsen their liver disease.

  2. I’ll probably be the first person with the bad news. Start putting your things in order. Pneumonia will be the beginning of the end.

    Your days on this Earth are coming to a quick end.

    I lost 3 people with H-C. There is no cure. It is fatal.

    If you believe in Jesus…Try making ammends for the lifestyle you have chosen….One exception…blood transfusions.

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